De novo protein design

Technique · AI for Science · 1 item since Aug 2026

Designing new proteins, such as binders for a target, computationally from scratch.

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  1. Aug 18

    Claude runs wet-lab-validated protein design campaigns

    Using only open-source tools, Claude ran de novo binder campaigns against 15 targets and produced binders for 14 at a 26.8% hit rate (versus the 10-15% norm), validated by Adaptyv Bio and Twist Bioscience; Opus 5 also read raw NMR and LC-MS files to a 96.4% purity call in under 25 minutes.